The Q Exactive instrument can easily handle routine applications in proteomics from bottom-up protein ID to semiquantitative isotopic labeling analyses to targeted quantification experiments. At the same time, its innovative HR/AM Quanfirmation™ capability makes the Q Exactive mass spectrometer the ideal solution for fast, easy residue screening and quantification in food safety, environmental and toxicology labs. The Q Exactive MS is superbly suited to routine bioanalytical quantitation of both large and small molecules; the superior quality of its HR/AM data supplying an added degree of confidence to these analyses. It is also ideal for pharmaceutical research laboratories looking for confident ID and precise quantification of metabolites, impurities, leachables and extractables. In short, the versatility and high data quality of the Q Exactive LC-MS/MS system make it a valuable addition to any modern laboratory.

UNIQUE FEATURES OF THE Q EXACTIVE

Identify, quantify and confirm with unmatched confidence using the Q Exactive mass spectrometer.

• Resolving power up to 140,000
• Maximum scan speed 12 Hz
• Intra-scan dynamic range > 5000:1
• Quadrupole mass filter
• Spectral multiplexing for enhanced duty cycle
• S-Lens ion source for increased sensitivity

Mass Range

m/z 50-6,000

Max Resolving Power

140,000 @ m/z 200

Max Scan Rate

Up to 12 Hz at resolution setting of 17,500 @ m/z 200

Mass Accuracy

Internal: < 1 ppm RMS External: < 3 ppm RMS under defined conditions

Sensitivity

Full MS: 500 fg Buspirone on column S/N 100:1 SIM: 50 fg Buspirone on column S/N 100:1

Dynamic Range

5000:1

Polarity Switching

One full cycle in < 1 sec (one full scan positive mode and one full scan negative mode at resolution setting of 35,000)

Multiplexity

Up to 10 precursors/scan

Analog Inputs

One (1) analog input (0 – 1 V) One (1) analog (0 – 10 V)